venofer dosing calculator

Applies only to oral form of both agents. DOSAGE AND ADMINISTRATION: Venofer must only be administered intravenously either by slow injection or by infusion. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. Assessing new treatment options, Intravenous iron-dextran: therapeutic and experimental possibilities. Separate by 2 hr. Please note that once you have closed the PDF you need to click on the Calculate button before you try opening it again, otherwise the input and/or results may not appear in the pdf. Discard unused portion. Med J Aust; 193(9):525-32. Copyright 2021 GlobalRPH - Web Development by, Calculation of the Total Iron Deficit Alternative equation. Deferoxamine chelates iron. Pasricha SR, Flecknoe-Brown SC, Allen KJ, Gibson PR, McMahon LP, Olynyk JK, Roger SD, Savoia HF, Tampi R, Thomson AR, Wood EM, Robinson KL. iron sucrose decreases levels of levofloxacin by inhibition of GI absorption. This calculator will help pinpoint potential causes of anemia based on Found in multiple references. The initial hemoglobin rise is more rapid with parenteral iron but on the long term (12 weeks), both therapies reach similar levels of hemoglobin. PDF IRON PRODUCT CHOICE AND DOSE CALCULATION - Blood Hanson DB, Hendeles L. Guide to total dose intravenous iron dextran therapy. iron sucrose decreases levels of penicillamine by inhibition of GI absorption. Am J Hosp Pharm. Corrected Sodium and Effective Osmolality. Monitor Closely (1)iron sucrose decreases levels of ibandronate by inhibition of GI absorption. Use Caution/Monitor. Iron Sucrose Monograph for Professionals - Drugs.com Dilute Venofer in a maximum of 250 mL of 0.9% NaCl [see How Supplied/Storage and Handling (16.2).] Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. Shirley, NY: American Regent, Inc.; 9/2020. 3) Bayraktar UD, Bayraktar S. (2010) Treatment of iron deficiency anemia associated with gastrointestinal tract diseases. 20 mg/mL for Iron sucrose; 5 mg/mL for Ferric gluconate. Monitor Closely (1)lansoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Avoid or Use Alternate Drug. iron sucrose decreases levels of demeclocycline by inhibition of GI absorption. UpToDate. IV iron sucrose (Venofer) given as divided dosages, and low molecular weight iron dextran (CosmoFer) this can be given as divided dose or as a total dose infusion . USES: This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. vonoprazan will decrease the level or effect of iron sucrose by inhibition of GI absorption. Applies only to oral form of both agents. All Rights Reserved. DOSAGE AND ADMINISTRATION: Oral iron should be discontinued prior to administration of INFeD. 1. Ferric gluconate: 12.5 mg/mL. lansoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Finally, a 400-mg dose by 2-hour infusion was examined in 35 patients, but 2 patients experienced such symptoms as hypotension, nausea, and lower back pain. Iron Deficiency Calculator - MDApp Use Caution/Monitor. Talk to your pharmacist for more details.During pregnancy, this medication should be used only when clearly needed. J Lab Clin Med. Applies only to oral form of both agents. 1. Indications: Feraheme is indicated for the treatment of iron deficiency anemia (IDA) in adult patients: who have intolerance to oral iron or have had unsatisfactory response to oral iron or who have chronic kidney disease (CKD). This site complies with the HONcode standard for trust- worthy health information: verify here. Each costs about $0.46 to $0.55 per mg of iron. iron sucrose decreases levels of oxytetracycline by inhibition of GI absorption. -Hgb deficit (grams) = Hgb deficit (g/dL) x blood volume (dL) -Iron deficit (mg) = Hgb deficit (grams) x 3.3 (mg Fe/g Hgb) [Note: 3.3 x 0.65 = 2.145] -Volume of parenteral iron product req'd (mL) = [Iron deficit (mg)] / C(mg/mL) Final calculations: -Hgb iron deficit (mg) = weight (kg) x (14 - Hgb) x (2.145) -Volume of product required (mL) = [weight (kg)x (14 - Hgb) x (2.145)] / C Where C= concentration of elemental iron (mg/ml) in the product being used: Iron dextran: 50 mg/mL. IDA diagnosis is based on full blood examination and on the serum ferritin level. Equations used: 1] Calculation of the Total Iron Deficit: Total iron deficit [mg] = body weight [kg] x (target Hb-actual Hb) [g/dl] x 2.4 + depot iron [mg]. Applies only to oral form of both agents. Minor/Significance Unknown. In less advanced cases of iron deficiency, increases in dietary intake of iron may be sufficient. Intravenous iron-dextran: therapeutic and experimental possibilities, Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations, Diagnosis and management of iron deficiency anaemia: a clinical update. 2010;18(3). When administered via infusion, dilute up to 750 mg of iron in no more than 250 mL of sterile 0.9% sodium chloride injection, USP, such that the concentration of the infusion is not less than 2 mg of iron per mL and administer over at least 15 minutes. Adding plans allows you to compare formulary status to other drugs in the same class. (1970) Intravenous iron-dextran: therapeutic and experimental possibilities. Avoid or Use Alternate Drug. Sodium ferric gluconate complex injection [ Ferrlecit ] [package insert] - Elemental iron: 12.5 mg/mL (5 mL). Minor/Significance Unknown.iron sucrose increases levels of calcium acetate by enhancing GI absorption. Dosing for patients who weigh 50 kg or more For patients weighing 50 kg (110 lb) or more: Give Injectafer in two doses separated by at least 7 days. Use Caution/Monitor. Minor/Significance Unknown.iron sucrose increases levels of calcium chloride by enhancing GI absorption. Monitor Closely (1)aluminum hydroxide will decrease the level or effect of iron sucrose by increasing gastric pH. There are three fields in the parenteral iron replacement for iron deficiency anemia calculator: Weight can be input in either lbs or kilograms and the required transformations are performed by the calculator. Medically reviewed by Drugs.com. Since this is less than the threshold of total dose of 20 mg/kg, the deficit can be eliminated with a single infusion. Iron Sucrose Dosage Guide + Max Dose, Adjustments - Drugs.com PRECAUTIONS: Before using iron sucrose, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. -Hgb deficit (grams) = Hgb deficit (g/dL) x blood volume (dL) -Iron deficit (mg) = Hgb deficit (grams) x 3.3 (mg Fe/g Hgb) [Note: 3.3 x 0.65 = 2.145] Monitor Closely (1)iron sucrose decreases levels of penicillamine by inhibition of GI absorption. Avoid or Use Alternate Drug. Symptoms associated with Venofer total dosage or infusing too rapidly included hypotension, dyspnea, headache, vomiting, nausea, dizziness, joint aches, paresthesia, abdominal and muscle pain, edema and cardiovascular collapse. Parenteral iron dextran therapy. aluminum hydroxide will decrease the level or effect of iron sucrose by increasing gastric pH. Your list will be saved and can be edited at any time. PDF Protocol for the use of Intravenous Iron Dextran (CosmoFer Modify Therapy/Monitor Closely. Intravenous iron replacement can take place as total dose (as in the case of iron-dextran or iron carboxymaltose) or as split dose (in the case of iron sucrose). Use Caution/Monitor. This drug is available at the lowest co-pay. Calcs that help predict probability of a disease, Subcategory of 'Diagnosis' designed to be very sensitive, Disease is diagnosed: prognosticate to guide treatment. Have resuscitation equipment and personnel trained in the detection and treatment of anaphylactic-type reactions readily available during INFeD administration. The dosing of Monofer was performed according to the Simplified Table as described in section 4.2 above and dosing of iron sucrose was calculated according to Ganzoni and administered as 200 mg infusions. Applies only to oral form of both agents. Each mL contains 20 mg of elemental iron. DOSAGE AND ADMINISTRATION: The recommended dose of Feraheme is an initial 510 mg dose followed by a second 510 mg dose 3 to 8 days later. Monitor Closely (1)pantoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. feasible, Maximum total cumulative iron sucrose dose administered in 14 days is 1000 mg elemental iron. Copyright 2014 - 2023 The Calculator .CO |All Rights Reserved|Terms and Conditions of Use, Intravenous iron-dextran: therapeutic and experimental possibilities, Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations, Treatment of iron deficiency anemia associated with gastrointestinal tract diseases, Diagnosis and management of iron deficiency anaemia: a clinical update. Serious - Use Alternative (1)iron sucrose decreases levels of ofloxacin by inhibition of GI absorption. FERAHEME Dosing & Administration - Feraheme Maximum recommended single dose: 300 mg (See Prescriber's Orders). Most studies have used IV iron sucrose (maximum dose of 200 mg per setting) or ferric carboxymaltose (maximum dose of 1000 mg per week). When to Use Weight lbs Target hemoglobin g/dL Actual hemoglobin g/dL Iron stores Use 500 mg for adults and children 35 kg; use 15 mg/kg if <35 kg mg Result: Please fill out required fields. Minor/Significance Unknown. *Repeat dose if iron deficiency anemia reoccurs. Monitor Closely (1)iron sucrose will decrease the level or effect of omadacycline by inhibition of GI absorption. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvdmVub2Zlci1pcm9uLXN1Y3Jvc2UtMzQyMTYy, View explanations for tiers and Here are the steps to follow for using this drug dosage calculator: First, enter the value of your Weight and choose the unit of measurement from the drop-down menu. Applies only to oral form of both agents. Koch TA, Myers J, Goodnough LT. Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations. Observed Hb = the patients current hemoglobin in g/dl. Serious - Use Alternative (1)iron sucrose decreases levels of doxycycline by inhibition of GI absorption. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Information last revised December 2022. Avoid or Use Alternate Drug. Where C= concentration of Use Caution/Monitor. Serious - Use Alternative (1)iron sucrose decreases levels of minocycline by inhibition of GI absorption. Applies only to oral form of both agents. This may be helped by giving the medication more slowly or at a lower dose. To provide clinicians with evidence-based guidance for iron therapy dosing in patients with iron deficiency anemia (IDA), we conducted a study examining the benefits of a higher cumulative dose of intravenous (IV) iron than what is typically administered. Please confirm that you would like to log out of Medscape. The weight of the patient is taken into account in order to estimate iron stores, while haemoglobin is required as both current measured and target. Applies only to oral form of both agents. Venofer must only be administered intravenously either by slow injection or by infusion. Use Caution/Monitor. Total cumulative Venofer dose = number of 100mg ampoules for Hb increase. Give each dose as 15 mg/kg body weight for a total cumulative dose not to exceed 1500 mg of iron per course. Coadministration of ciprofloxacin with multivalent cation-containing products may reduce the bioavailability of ciprofloxacin by 90%. Applies only to oral form of both agents. Minor/Significance Unknown. Applies only to oral form of both agents. 1) Ganzoni AM. Iron sucrose | Drugs | BNF | NICE For all products, slow initial infusion is prudent; the patient is observed closely for infusion reactions. Treatment of anemia due to iron deficiency. The primary endpoint was the proportion of patients with . Applies only to oral form of both agents. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. Patients with a history of drug allergy or multiple drug allergies may be at increased risk of anaphylactic-type reactions to INFeD. In a randomized, open-label, dose-ranging trial for iron maintenance treatment with Venofer in pediatric patients with CKD on stable erythropoietin therapy [see Clinical Studies ( 14.7)], at least one adverse reaction was experienced by 57% (27/47) of the patients receiving Venofer 0.5 mg/kg, 53% (25/47) of the patients receiving Venofer 1 mg . Use Caution/Monitor. Minor/Significance Unknown. Applies only to oral form of both agents. Drug: Comments: A: Acyclovir 1: Dose using a 40% adjusted body weight; Amikacin 2: Dose using a 40% adjusted body weight; Amphotericin B (liposomal) 3 Consider capping body weight to 100 kg; Atracurium 4: Dose using ideal body weight; The use of ideal body weight has been shown to be associated with a more predictable muscle strength recovery within 60 minutes and a lack of need for antagonism . Applies only to oral form of both agents.

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